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Great for tacos, sandwiches, baked potatoes or just by itself.
Place brisket in a gallon size Ziploc bag. Pour liquid smoke over the brisket. Add onion, salt and garlic salt. Seal the bag and put it into the refrigerator to marinate for a minimum of 3 hours, turning occasionally to redistribute the liquid.
Preheat oven to 275 F.
Remove brisket from the marinade and place it on a large piece of heavy duty foil. Discard the marinade mixture. Pour Worcestershire sauce over the brisket and fold the foil around the brisket and seal it up. Place it in a roasting pan.
Bake for 5 hours. Then pull it out of the oven, unfold foil and pour barbecue sauce evenly over brisket. Bake for 1 more hour uncovered.
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